Motif ID: SOX{8,9,10}.p2

Z-value: 2.248

Transcription factors associated with SOX{8,9,10}.p2:

NameEntrezDescription
Sox10 20665 SRY-box containing gene 10
Sox8 20681 SRY-box containing gene 8
Sox9 20682 SRY-box containing gene 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Sox8chr17_-_25707599-0.892.0e-13Click!
Sox10chr15_-_78994753-0.661.2e-05Click!
Sox9chr11_+_1126435010.625.1e-05Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr7_-_111001598 42.856 NM_008221
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr7_-_56892061 37.311 NM_001005232
Dbx1
developing brain homeobox 1
chr6_-_12699189 25.772 NM_001164805
Thsd7a
thrombospondin, type I, domain containing 7A
chr4_+_154335029 21.832 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chrX_+_108009728 19.474 NM_008901
Pou3f4
POU domain, class 3, transcription factor 4
chr7_-_110991602 19.348 NM_008219
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr13_-_56353523 14.496 NM_010896
Neurog1
neurogenin 1
chr1_-_12980994 14.287 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr10_+_17516024 12.290 NM_138628
Txlnb
taxilin beta
chr2_+_181498036 12.085 NM_001171615
Myt1
myelin transcription factor 1
chr2_+_25036276 10.902 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr13_-_117099629 10.694 NM_021459
Isl1
ISL1 transcription factor, LIM/homeodomain
chr5_+_48374328 9.915 NM_178804
Slit2
slit homolog 2 (Drosophila)
chr7_+_106614513 9.906 NM_028145
Klhl35
kelch-like 35 (Drosophila)
chr1_-_140739020 9.689 NM_001025565
NM_001042577
Lhx9

LIM homeobox protein 9

chr1_+_134212642 9.482 NM_001195025
NM_028778
Nuak2

NUAK family, SNF1-like kinase, 2

chr2_-_73613381 9.344 NM_001113246
NM_001166603
Chn1

chimerin (chimaerin) 1

chr13_-_54789148 8.965 NM_001146025
NM_001146026
NM_134064
Rnf44


ring finger protein 44


chr5_+_111846284 8.757 Mn1
meningioma 1
chr18_-_75120759 8.645 NM_010720
Lipg
lipase, endothelial
chr10_-_61246611 8.369 NM_207000
H2afy2
H2A histone family, member Y2
chr4_+_13670582 8.233 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_93905557 8.105 Spag9
sperm associated antigen 9
chr4_+_48598013 7.711 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr13_-_97440734 7.656 NM_008255
Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr16_+_18392675 7.488 Arvcf
armadillo repeat gene deleted in velo-cardio-facial syndrome
chr16_+_52031733 7.331 Cblb
Casitas B-lineage lymphoma b
chr6_+_64992810 7.211 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_19198994 7.114 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr13_-_60278723 7.095 Gas1
growth arrest specific 1
chr5_-_138721164 7.022 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr14_-_104867215 7.016 NM_011143
Pou4f1
POU domain, class 4, transcription factor 1
chr1_-_173957316 6.828 NM_033509
Vangl2
vang-like 2 (van gogh, Drosophila)
chr6_-_31513817 6.827 NM_013723
Podxl
podocalyxin-like
chr4_-_117169519 6.806 NM_025739
Rnf220
ring finger protein 220
chr15_+_98465193 6.667 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr6_+_83087016 6.589 NM_009106
NM_133641
Rtkn

rhotekin

chr16_+_52031704 6.536 Cblb
Casitas B-lineage lymphoma b
chr18_-_16966954 6.401 Cdh2
cadherin 2
chr18_-_43552694 6.360 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr4_+_122673318 6.317 NM_008506
Mycl1
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr5_-_67490295 6.248 NM_008888
Phox2b
paired-like homeobox 2b
chr10_+_43298969 6.153 NM_009846
Cd24a
CD24a antigen
chr8_+_125935441 6.092 NM_023279
Tubb3
tubulin, beta 3
chr15_-_95358674 6.083 Nell2
NEL-like 2 (chicken)
chr4_-_109960078 6.081 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_55388955 6.043 NM_027397
Isl2
insulin related protein 2 (islet 2)
chr13_-_96388378 5.896 NM_010169
F2r
coagulation factor II (thrombin) receptor
chr10_+_57206184 5.882 NM_008297
Hsf2
heat shock factor 2
chr2_-_153067043 5.851 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr16_+_17070249 5.778 NM_023249
Ypel1
yippee-like 1 (Drosophila)
chr14_+_27852148 5.772 NM_134437
Il17rd
interleukin 17 receptor D
chr11_+_23978110 5.738 Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_25292105 5.618 NM_146183
Zfp428
zinc finger protein 428
chr9_+_64988960 5.592 NM_008988
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr5_+_28492235 5.457 NM_010134
En2
engrailed 2
chr10_-_75395207 5.400 NM_008606
Mmp11
matrix metallopeptidase 11
chr1_-_33871349 5.360 Zfp451
zinc finger protein 451
chr7_+_30088984 5.348 NM_013874
Dpf1
D4, zinc and double PHD fingers family 1
chrX_+_96331434 5.345 NM_010110
Efnb1
ephrin B1
chr11_+_23978029 5.341 NM_001159289
NM_016707
Bcl11a

B-cell CLL/lymphoma 11A (zinc finger protein)

chrX_-_137077133 5.250 Tsc22d3
TSC22 domain family, member 3
chr1_-_135975681 5.242 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr1_+_135142673 5.181 NM_001160268
NM_182930
Plekha6

pleckstrin homology domain containing, family A member 6

chr4_+_111087610 5.164 NM_026279
Bend5
BEN domain containing 5
chr2_-_30329737 5.151 Ier5l
immediate early response 5-like
chr15_-_26825266 5.148 NM_176959
Fbxl7
F-box and leucine-rich repeat protein 7
chr11_+_43495499 5.098 NM_001164231
NM_027557
Pwwp2a

PWWP domain containing 2A

chr14_+_59820284 5.047 Rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr1_+_122499031 4.987 NM_010133
En1
engrailed 1
chr2_-_130985746 4.950 NM_026091
1700037H04Rik
RIKEN cDNA 1700037H04 gene
chr15_+_98620287 4.942 NM_021279
Wnt1
wingless-related MMTV integration site 1
chr14_-_109313298 4.922 Slitrk1
SLIT and NTRK-like family, member 1
chr4_+_13670425 4.892 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_51942043 4.762 NM_011817
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr6_-_47763309 4.747 Pdia4
protein disulfide isomerase associated 4
chr5_+_143722032 4.725 NM_007984
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr19_+_40905768 4.709 NM_172839
Ccnj
cyclin J
chr2_-_118375365 4.641 NM_138313
Bmf
BCL2 modifying factor
chr13_-_96388412 4.621 F2r
coagulation factor II (thrombin) receptor
chr11_-_113613040 4.591 NM_001163346
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr6_-_71582871 4.591 NM_001038695
Kdm3a
lysine (K)-specific demethylase 3A
chr4_+_129190872 4.567 Marcksl1
MARCKS-like 1
chr7_+_128177958 4.556 NM_021554
Mettl9
methyltransferase like 9
chr3_+_94282235 4.520 Celf3
VCUGBP, Elav-like family member 3
chr8_-_94325138 4.445 NM_008393
Irx3
Iroquois related homeobox 3 (Drosophila)
chr15_-_90880241 4.441 NM_001109040
NM_001109041
NM_001109042
NM_016705
Kif21a



kinesin family member 21A



chr4_-_131604821 4.402 NM_001128606
Epb4.1
erythrocyte protein band 4.1
chr1_+_134942609 4.397 Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr13_-_54789064 4.365 Rnf44
ring finger protein 44
chr12_-_36769054 4.355 NM_025359
Tspan13
tetraspanin 13
chr6_-_148893155 4.350 Fam60a
family with sequence similarity 60, member A
chr3_+_132754791 4.318 NM_027927
Ints12
integrator complex subunit 12
chr10_+_79612410 4.315 Midn
midnolin
chr4_-_21612991 4.246 NM_001080771
Prdm13
PR domain containing 13
chr2_-_65405546 4.224 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_-_83071206 4.151 Wbp1
WW domain binding protein 1
chr2_+_91366928 4.150 Ckap5
cytoskeleton associated protein 5
chr15_-_95358989 4.134 Nell2
NEL-like 2 (chicken)
chr3_+_145541951 4.127


chr1_-_173957407 4.107 Vangl2
vang-like 2 (van gogh, Drosophila)
chr6_+_64992584 4.070 NM_007958
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_-_36046961 4.057 NM_001142744
NM_001142745
NM_028476
Atat1


alpha tubulin acetyltransferase 1


chr3_-_66100663 4.044 NM_145820
Veph1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr2_+_14976877 4.020 NM_029466
Arl5b
ADP-ribosylation factor-like 5B
chr7_-_112936063 4.007 NM_001162943
Dchs1
dachsous 1 (Drosophila)
chr5_+_125343060 3.995 NM_001081750
Zfp664
zinc finger protein 664
chr2_-_30329717 3.975 NM_030244
Ier5l
immediate early response 5-like
chr14_-_52723590 3.938 NM_001170981
NM_001170982
NM_001170983
NM_001170984
NM_016884
Hnrnpc




heterogeneous nuclear ribonucleoprotein C




chr19_-_47036782 3.916 NM_029810
Nt5c2
5'-nucleotidase, cytosolic II
chr5_-_135028197 3.906 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr1_-_77511653 3.900 NM_007936
Epha4
Eph receptor A4
chr11_-_86621074 3.899 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr12_-_101121613 3.887 NM_030172
2610021K21Rik
RIKEN cDNA 2610021K21 gene
chr5_-_92512683 3.873 NM_001080795
NM_011816
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr4_+_129190877 3.873 Marcksl1
MARCKS-like 1
chr6_+_37820779 3.868 NM_145076
Trim24
tripartite motif-containing 24
chr3_+_34548916 3.858 NM_011443
Sox2
SRY-box containing gene 2
chr19_+_37281988 3.852 NM_001164336
NM_001164337
NM_027314
March5


membrane-associated ring finger (C3HC4) 5


chr1_-_153347884 3.831 NM_011277
Rnf2
ring finger protein 2
chr6_+_17015159 3.829 Tes
testis derived transcript
chrX_+_93651684 3.829 NM_001159627
NM_181273
Heph

hephaestin

chr16_-_45724422 3.810 NM_019754
Tagln3
transgelin 3
chr1_-_145851257 3.807 NM_009061
Rgs2
regulator of G-protein signaling 2
chr7_+_119167048 3.793 Usp47
ubiquitin specific peptidase 47
chr12_-_36883307 3.784 NM_025840
Bzw2
basic leucine zipper and W2 domains 2
chr14_+_76245136 3.782 Tpt1
tumor protein, translationally-controlled 1
chr9_+_7764067 3.771 NM_133739
Tmem123
transmembrane protein 123
chr7_+_82600419 3.748 NM_029332
Akap13
A kinase (PRKA) anchor protein 13
chr4_-_77857594 3.746 Ptprd
protein tyrosine phosphatase, receptor type, D
chr2_-_103637714 3.743 Caprin1
cell cycle associated protein 1
chr16_+_78301923 3.728 NM_001025192
NM_009988
Cxadr

coxsackie virus and adenovirus receptor

chr7_-_11080687 3.725 NM_009577
Zik1
zinc finger protein interacting with K protein 1
chr6_-_30643681 3.707 NM_031998
Tsga14
testis specific gene A14
chr9_-_36954842 3.688 NM_001029838
Pknox2
Pbx/knotted 1 homeobox 2
chr4_-_134828699 3.685 Clic4
chloride intracellular channel 4 (mitochondrial)
chr9_+_108410335 3.684 NM_133794
Qars
glutaminyl-tRNA synthetase
chr9_+_72655019 3.677 NM_175485
Prtg
protogenin homolog (Gallus gallus)
chr8_+_63703064 3.671 Sh3rf1
SH3 domain containing ring finger 1
chr13_+_14156038 3.670 NM_194262
NM_198122
Arid4b

AT rich interactive domain 4B (RBP1-like)

chr4_+_118781405 3.636 Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr2_-_29701764 3.635 Gm3088
predicted gene 3088
chrX_+_104115963 3.624 NM_175271
Lpar4
lysophosphatidic acid receptor 4
chr7_-_134758707 3.624 Zfp629
zinc finger protein 629
chrX_+_54307050 3.623 Htatsf1
HIV TAT specific factor 1
chr12_-_40763924 3.606 NM_007487
Arl4a
ADP-ribosylation factor-like 4A
chr9_+_122832164 3.585 NM_009544
Zfp105
zinc finger protein 105
chr10_-_119913204 3.561 Hmga2
high mobility group AT-hook 2
chr16_-_96349334 3.532 Hmgn1
high mobility group nucleosomal binding domain 1
chr5_+_147042806 3.525 Cdk8
cyclin-dependent kinase 8
chr5_+_36236113 3.520 Afap1
actin filament associated protein 1
chr11_+_44430784 3.519


chr7_+_4691716 3.507 NM_001115018
NM_146177
Suv420h2

suppressor of variegation 4-20 homolog 2 (Drosophila)

chr5_-_103640272 3.473 NM_001081567
NM_009158
Mapk10

mitogen-activated protein kinase 10

chr7_+_88005861 3.457 Zscan2
zinc finger and SCAN domain containing 2
chr3_+_145784635 3.450 NM_134160
Mcoln3
mucolipin 3
chr2_+_91366966 3.432 Ckap5
cytoskeleton associated protein 5
chr8_+_72346327 3.432 NM_020028
Lpar2
lysophosphatidic acid receptor 2
chr6_-_39156609 3.413 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr13_+_88961161 3.407 Edil3
EGF-like repeats and discoidin I-like domains 3
chr1_+_131170034 3.400 Thsd7b
thrombospondin, type I, domain containing 7B
chr8_+_125935470 3.395 Tubb3
tubulin, beta 3
chr19_-_46114019 3.379 NM_010697
Ldb1
LIM domain binding 1
chr5_-_115750940 3.334 Dynll1
dynein light chain LC8-type 1
chr7_+_109118687 3.320 Numa1
nuclear mitotic apparatus protein 1
chr4_+_108132602 3.302 Zcchc11
zinc finger, CCHC domain containing 11
chr9_-_110526866 3.287 NM_026012
Nradd
neurotrophin receptor associated death domain
chr9_-_50535949 3.285 NM_178118
Dixdc1
DIX domain containing 1
chr8_+_108939247 3.260 Zfp90
zinc finger protein 90
chr4_+_106233632 3.253 NM_053272
Dhcr24
24-dehydrocholesterol reductase
chr2_+_152561983 3.246 NM_010495
Id1
inhibitor of DNA binding 1
chr12_+_17273358 3.243 NM_027959
Pdia6
protein disulfide isomerase associated 6
chr8_-_48373564 3.215 Stox2
storkhead box 2
chr8_+_3493117 3.214 NM_080461
Zfp358
zinc finger protein 358
chr11_+_60513191 3.188 NM_001159404
NM_001159405
NM_008502
Llgl1


lethal giant larvae homolog 1 (Drosophila)


chr17_+_30142111 3.186 Zfand3
zinc finger, AN1-type domain 3
chr5_+_31191349 3.180 NM_001048192
Agbl5
ATP/GTP binding protein-like 5
chr10_-_62801726 3.174 NM_001159590
NM_019812
NM_001159589
Sirt1


sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)


chr7_-_146768633 3.172 NM_183248
Nkx6-2
NK6 homeobox 2
chr2_-_37558818 3.163 Strbp
spermatid perinuclear RNA binding protein
chr5_+_34326081 3.156 NM_001033458
Gm1673
predicted gene 1673
chrX_+_55283804 3.129 NM_009575
Zic3
zinc finger protein of the cerebellum 3
chr2_-_179777080 3.128 NM_011969
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr12_-_35213738 3.123 NM_024124
Hdac9
histone deacetylase 9
chr11_+_86922732 3.119 NM_025377
Fam33a
family with sequence similarity 33, member A
chr13_-_55589377 3.118 NM_001177371
NM_001177372
NM_019813
Dbn1


drebrin 1


chr11_-_116704762 3.118 NM_033398
Jmjd6
jumonji domain containing 6
chr12_+_112776424 3.052 Eif5
eukaryotic translation initiation factor 5
chr1_+_122498985 3.039 En1
engrailed 1
chr8_-_4325051 3.017 NM_010485
Elavl1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr19_-_7114388 3.002 NM_016737
Stip1
stress-induced phosphoprotein 1
chr9_+_108998083 3.001 Plxnb1
plexin B1
chr1_-_183950050 2.980 NM_001083120
NM_001083121
NM_008680
NM_010135
Enah



enabled homolog (Drosophila)



chr9_+_40609317 2.972 NM_031165
Hspa8
heat shock protein 8
chr1_-_170361525 2.971 Pbx1
pre B-cell leukemia transcription factor 1
chr5_-_123350242 2.968 NM_013910
Kdm2b
lysine (K)-specific demethylase 2B
chr12_+_25393083 2.968 NM_009104
Rrm2
ribonucleotide reductase M2
chr5_+_125343129 2.944 Zfp664
zinc finger protein 664
chr16_-_17125198 2.943 NM_183287
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_+_31801595 2.936 NM_028231
Kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.32 2.09e-22 GO:0010468 regulation of gene expression
2.41 1.07e-21 GO:0051252 regulation of RNA metabolic process
2.33 3.33e-21 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.29 1.45e-20 GO:0010556 regulation of macromolecule biosynthetic process
2.24 3.43e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.37 3.84e-20 GO:0006355 regulation of transcription, DNA-dependent
2.22 1.01e-19 GO:0051171 regulation of nitrogen compound metabolic process
2.03 4.78e-19 GO:0060255 regulation of macromolecule metabolic process
2.07 5.61e-19 GO:0032502 developmental process
1.98 2.95e-18 GO:0031323 regulation of cellular metabolic process
2.11 3.54e-18 GO:0007275 multicellular organismal development
2.17 4.07e-18 GO:0031326 regulation of cellular biosynthetic process
1.97 8.62e-18 GO:0080090 regulation of primary metabolic process
2.17 1.18e-17 GO:0048856 anatomical structure development
2.14 1.41e-17 GO:0009889 regulation of biosynthetic process
2.13 1.49e-16 GO:0090304 nucleic acid metabolic process
1.85 3.99e-16 GO:0019222 regulation of metabolic process
2.22 4.62e-16 GO:0016070 RNA metabolic process
1.97 1.79e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.82 4.14e-15 GO:0007399 nervous system development
2.16 4.21e-15 GO:0048731 system development
2.37 5.10e-14 GO:0006351 transcription, DNA-dependent
2.36 5.80e-14 GO:0032774 RNA biosynthetic process
1.86 7.00e-14 GO:0034641 cellular nitrogen compound metabolic process
1.82 3.94e-13 GO:0006807 nitrogen compound metabolic process
1.68 9.08e-13 GO:0044260 cellular macromolecule metabolic process
2.02 9.76e-13 GO:0010467 gene expression
2.09 2.72e-10 GO:0030154 cell differentiation
1.41 3.62e-10 GO:0050794 regulation of cellular process
2.05 7.46e-10 GO:0048869 cellular developmental process
2.88 1.15e-09 GO:0048699 generation of neurons
1.93 1.19e-09 GO:0034645 cellular macromolecule biosynthetic process
1.37 1.38e-09 GO:0065007 biological regulation
1.92 2.10e-09 GO:0009059 macromolecule biosynthetic process
1.55 2.99e-09 GO:0043170 macromolecule metabolic process
1.38 4.07e-09 GO:0050789 regulation of biological process
2.75 5.11e-09 GO:0022008 neurogenesis
1.93 4.01e-08 GO:0071842 cellular component organization at cellular level
1.89 8.20e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.43 1.64e-07 GO:0044237 cellular metabolic process
1.89 1.88e-07 GO:0048523 negative regulation of cellular process
3.04 2.86e-07 GO:0030182 neuron differentiation
1.69 6.06e-07 GO:0044249 cellular biosynthetic process
1.80 8.69e-07 GO:0048519 negative regulation of biological process
2.52 1.04e-06 GO:0009790 embryo development
1.66 1.13e-06 GO:0009058 biosynthetic process
1.70 1.71e-06 GO:0016043 cellular component organization
1.68 1.85e-06 GO:0071840 cellular component organization or biogenesis
2.10 2.34e-06 GO:0009653 anatomical structure morphogenesis
1.39 2.39e-06 GO:0044238 primary metabolic process
1.93 3.34e-06 GO:0048513 organ development
2.02 8.11e-06 GO:0006996 organelle organization
5.63 1.30e-05 GO:0021915 neural tube development
2.99 2.34e-05 GO:0048598 embryonic morphogenesis
1.20 3.44e-05 GO:0009987 cellular process
2.77 6.36e-05 GO:0043009 chordate embryonic development
2.30 6.84e-05 GO:0048468 cell development
2.46 6.89e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.39 7.90e-05 GO:0031327 negative regulation of cellular biosynthetic process
2.73 9.18e-05 GO:0009792 embryo development ending in birth or egg hatching
2.33 1.58e-04 GO:0009890 negative regulation of biosynthetic process
7.78 1.92e-04 GO:0045665 negative regulation of neuron differentiation
2.36 2.16e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.30 2.91e-04 GO:0008152 metabolic process
2.39 3.05e-04 GO:0010629 negative regulation of gene expression
2.12 3.39e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.60 3.85e-04 GO:0035239 tube morphogenesis
2.91 4.75e-04 GO:0006325 chromatin organization
1.63 5.29e-04 GO:0048522 positive regulation of cellular process
1.39 6.40e-04 GO:0032501 multicellular organismal process
1.57 8.32e-04 GO:0048518 positive regulation of biological process
3.21 9.04e-04 GO:0002009 morphogenesis of an epithelium
2.40 1.07e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.13 1.13e-03 GO:2000026 regulation of multicellular organismal development
2.73 1.18e-03 GO:0048666 neuron development
2.98 1.29e-03 GO:0035295 tube development
2.28 1.40e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.36 1.56e-03 GO:0051253 negative regulation of RNA metabolic process
3.02 1.69e-03 GO:0045596 negative regulation of cell differentiation
2.50 1.71e-03 GO:0048646 anatomical structure formation involved in morphogenesis
4.86 1.74e-03 GO:0016331 morphogenesis of embryonic epithelium
2.16 1.79e-03 GO:0007049 cell cycle
2.00 2.01e-03 GO:0050793 regulation of developmental process
3.80 2.12e-03 GO:0060562 epithelial tube morphogenesis
2.77 2.12e-03 GO:0051093 negative regulation of developmental process
2.26 2.41e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02 2.67e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.07 3.35e-03 GO:0009888 tissue development
2.60 3.35e-03 GO:0007417 central nervous system development
2.75 3.69e-03 GO:0051960 regulation of nervous system development
2.88 3.81e-03 GO:0031175 neuron projection development
2.14 3.86e-03 GO:0045595 regulation of cell differentiation
3.14 3.92e-03 GO:0003002 regionalization
2.85 4.77e-03 GO:0050767 regulation of neurogenesis
4.78 5.05e-03 GO:0021953 central nervous system neuron differentiation
2.45 5.17e-03 GO:0051276 chromosome organization
1.98 5.24e-03 GO:0031324 negative regulation of cellular metabolic process
2.14 5.28e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.93 5.53e-03 GO:0009892 negative regulation of metabolic process
2.04 6.10e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.62 6.14e-03 GO:0060429 epithelium development
2.79 6.97e-03 GO:0007420 brain development
5.01 7.27e-03 GO:0035148 tube formation
3.02 7.28e-03 GO:0045664 regulation of neuron differentiation
2.11 7.69e-03 GO:0051254 positive regulation of RNA metabolic process
2.01 8.90e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.99 1.17e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.77 1.21e-02 GO:0016568 chromatin modification
2.63 1.24e-02 GO:0007389 pattern specification process
2.51 1.36e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.55 1.47e-02 GO:0060284 regulation of cell development
3.12 2.04e-02 GO:0000087 M phase of mitotic cell cycle
4.87 2.39e-02 GO:0001838 embryonic epithelial tube formation
4.87 2.39e-02 GO:0072175 epithelial tube formation
1.92 2.63e-02 GO:0031328 positive regulation of cellular biosynthetic process
5.18 3.40e-02 GO:0001841 neural tube formation
5.81 3.44e-02 GO:0001843 neural tube closure
2.53 3.58e-02 GO:0048729 tissue morphogenesis
5.71 3.97e-02 GO:0060606 tube closure
1.96 4.21e-02 GO:0010628 positive regulation of gene expression
1.88 4.31e-02 GO:0009891 positive regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.46 5.30e-29 GO:0005622 intracellular
1.94 2.47e-28 GO:0005634 nucleus
1.46 7.61e-27 GO:0044424 intracellular part
1.46 1.01e-18 GO:0043229 intracellular organelle
1.45 1.77e-18 GO:0043226 organelle
1.45 1.86e-14 GO:0043231 intracellular membrane-bounded organelle
1.44 2.58e-14 GO:0043227 membrane-bounded organelle
1.16 1.19e-08 GO:0005623 cell
1.16 1.19e-08 GO:0044464 cell part
1.81 5.24e-08 GO:0043228 non-membrane-bounded organelle
1.81 5.24e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.34 7.69e-08 GO:0005737 cytoplasm
1.91 5.61e-07 GO:0044428 nuclear part
1.93 1.16e-05 GO:0005856 cytoskeleton
1.78 8.11e-05 GO:0031974 membrane-enclosed lumen
1.86 8.41e-05 GO:0031981 nuclear lumen
1.44 1.65e-04 GO:0044446 intracellular organelle part
1.43 1.99e-04 GO:0044422 organelle part
1.73 5.11e-04 GO:0070013 intracellular organelle lumen
1.73 5.47e-04 GO:0043233 organelle lumen
2.33 8.89e-04 GO:0015630 microtubule cytoskeleton
1.75 1.35e-03 GO:0005829 cytosol
2.40 3.40e-03 GO:0005694 chromosome
1.90 6.12e-03 GO:0044430 cytoskeletal part
2.33 1.54e-02 GO:0044427 chromosomal part
9.68 3.08e-02 GO:0031519 PcG protein complex
9.68 3.08e-02 GO:0045120 pronucleus
2.84 4.47e-02 GO:0000228 nuclear chromosome
22.06 4.78e-02 GO:0005833 hemoglobin complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.42 2.46e-22 GO:0005488 binding
2.04 2.78e-14 GO:0003676 nucleic acid binding
1.58 8.20e-13 GO:0005515 protein binding
2.21 4.26e-12 GO:0003677 DNA binding
1.98 4.09e-07 GO:0046914 transition metal ion binding
2.35 1.02e-06 GO:0030528 transcription regulator activity
2.06 1.06e-06 GO:0008270 zinc ion binding
2.65 2.87e-05 GO:0019904 protein domain specific binding
2.06 1.14e-03 GO:0019899 enzyme binding
2.11 1.63e-03 GO:0001071 nucleic acid binding transcription factor activity
2.11 1.63e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
3.26 4.10e-03 GO:0003682 chromatin binding
1.42 5.20e-03 GO:0043167 ion binding
1.42 6.38e-03 GO:0046872 metal ion binding
2.04 1.04e-02 GO:0003723 RNA binding
1.41 1.10e-02 GO:0043169 cation binding
2.78 2.15e-02 GO:0019901 protein kinase binding
2.58 2.78e-02 GO:0019900 kinase binding